Perelman School of Medicine

A researcher holding up a petri dish with bacteria in it.

How a bacterium supports healing of chronic diabetic wounds

New research from Penn Medicine shows that a certain bug could be used to develop topical or bacterial-based treatments for patients with wounds that do not heal well on their own.

A newly identified immune checkpoint protein may lead to future cancer therapies

Penn Medicine researchers have found that knocking out a T cell’s CD5 gene greatly enhances the cell’s anticancer activity in a variety of preclinical cancer models.

A gloved hand dripping a substance from a pipette onto pills.

Charting a new frontier with psychedelic drugs

Penn Medicine’s Dominic Sisti is part of a group of experts including bioethicists, psychiatrists, and Indigenous scholars charting a path toward crafting guidelines for the ethical use of psychedelics.

A transcranial magnetic stimulation tool hovering over a human brain model.

New form of repetitive magnetic brain stimulation reduces treatment time for bipolar disorder

The potential bipolar disorder therapy can be completed in five days of treatment, compared to four-to-six weeks for standard transcranial magnetic simulation treatments.

A person with a sledgehammer working on the Breathing Room courtyard.

An empty outdoor space is transformed into a social garden

A 2023 Project for Progress initiative, the Breathing Room at Sayre High School was unveiled this spring.

When there’s money to lose, phone usage while driving drops

New research from Penn Medicine finds that feedback plus cash incentives designed with insights from behavioral science reduces phone use while driving.

Penn president J. Larry Jameson speaking at a microphone in London.

Showing up for Penn in London

A capacity audience attended an academic symposium in London titled “Frontiers of Knowledge and Discovery: Leading in a Changing World.”

3D illustration showing cross-section of the lipid nanoparticle carrying mRNA of the virus entering a human cell.

Penn pioneers a ‘one-pot platform’ to promptly produce mRNA delivery particles

New lipid platform enables rapid synthesis of molecules that can shuttle therapeutics for a range of diseases with a high degree of organ specificity.

Better survival rates from hospital-based donor care for lung transplants

A new study by Penn researchers has examined, for the first time, the differences in lung transplant graft outcomes from organs recovered from the two types of deceased organ donor care facilities operating in the United States.

Two nurses guiding a prone patient into a proton imaging machine.

The power of protons

Penn Medicine has treated more than 10,000 cancer patients at three proton therapy centers across the region, including the largest and busiest center in the world—while also leading the way in research to expand the healing potential of these positive particles.

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