Perelman School of Medicine

rendering of a brain and its different sections highlighted as different colors.

A link between memory and appetite in the brain to explain obesity

Penn Medicine researchers have found the hippocampal subnetwork, located within the memory center of the brain, is more dysregulated in patients with higher body mass indexes, leading to an inability to control or regulate eating habits.

Microscopic rendering of a white blood cell amongst red blood cells.

An immunotherapy strategy against all blood cancers

Researchers at Penn Medicine have demonstrated a new potential treatment using CAR T cell therapy using a CRISPR base-editing to develop a method called “epitope editing.”

People looking at modern art in a museum or gallery setting.

A summer studying the aesthetic brain

For third-year Olivia Kim, a PURM research experience with Penn neuroscientist Anjan Chatterjee allowed her to combine her love of neuroscience and art in a working lab.

Trading decisions are observable in the eyes of buyers and sellers

In a new collaborative study, PIK Professor Michael Platt models how the decision-making process unfolds in the brains of buyers and sellers considering a deal. These decisions were observable in eye movements and pupil dilation.

Carl June with a microphone in the Penn Medicine atrium with the celebratory flash mob.

Carl June on the boundless potential of CAR T cell therapy

In a Q & A, June, the Richard W. Vague Professor in Immunotherapy, and Daniel Baker, a fourth-year doctoral student in Penn’s Cell and Molecular Biology department, discuss how the treatment can extend to treating diseases beyond cancer.

Chasing the mysteries of microbiome communication in our bodies

Penn Medicine’s Maayan Levy and Christoph Thaiss, both assistant professors of microbiology, pursue an understanding of the the microbiome, the entirety of microbial organisms associated with the human body, and its relation to fundamental bodily systems.

For a new generation of antibiotics, scientists are bringing extinct molecules back to life

Marrying artificial intelligence with advanced experimental methods, Penn Engineering’s Machine Biology Group has mined the ancient past for future medical breakthroughs, bringing extinct molecules back to life.

Silicon wafer with chips lightinhg in neon light.

SCALAR: A microchip designed to transform the production of mRNA therapeutics and vaccines

Researchers have developed a platform that could rapidly accelerate the development of mRNA-based lipid nanoparticle vaccines and therapeutics at both the small and largescale, SCALAR.

Hard at work, crews make progress during summer construction

Ahead of the arrival of students, summer on campus bustles with construction teams advancing various building projects and maintenance work. Here, a look at what’s happening now.

Katalin Kariko and Drew Weissman wearing lab coats.

Long-awaited accolades for mRNA scientists Katalin Karikó and Drew Weissman

Katalin Karikó and Drew Weissman’s key mRNA discoveries more than 15 years earlier made COVID vaccines possible. Now the global public has opportunities to honor them.

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