Science & Technology

A scar might be a reminder of an accident or surgery, but the fibrous tissue that makes up a scar also forms after a heart attack and arises in solid tumors as well as in chronic diseases such as liver cirrhosis and muscular dystrophy. Implanted medical devices and materials are similarly surrounded by fibrous capsules that impede their function.  

The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises from modifications that occur at the level of gene, RNA and protein.

The Imagination Institute, based at the University of Pennsylvania’s Positive Psychology Center, has announced nearly $3 million worth of grants to researchers at 16 institutions. The grants are aimed at the development of better ways of assessing and promoting imagination and creativity.

Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.

WHO:     Danielle BassettSkirkanich Assistant Professor of InnovationDepartment of BioengineeringDepartment of Electrical and Systems EngineeringSchool of Engineering and Applied Science

Lyme disease cases are on the rise, with diagnoses occurring in areas that were historically Lyme-free. Scientists attribute the spread to the fact that populations of blacklegged ticks, which carry the bacteria that causes the disease, now flourish in areas once thought to be devoid of ticks.

By Sarah Welsh Nature versus nurture is an age-old question in biology, centering on whether a given trait is determined by an organism’s genes or by its environment. Most times the answer is “both,” but research at the University of Pennsylvania has found one trait in particular that is not easily described by either.

The role that attention plays in generating new and useful ideas is controversial among neuroscientists. Some neuroimaging studies have shown that creativity involves more cognitive control, or focused attention. Other studies have shown it involves less.

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility.

Investigators at a new University of Pennsylvania research center will focus on key physical principles that underpin cancer’s development and growth.