Health Sciences

Patients who received regional anesthesia during hip fracture surgery had moderately lower mortality and a significantly lower length of stay than those who received general anesthesia, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

Reporting in the June 25 issue of JAMA, researchers from Penn Medicine and other institutions found that 3D mammography—known as digital breast tomosynthesis— found significantly more invasive, or potentially lethal, cancers than a traditional mammogram alone and reduced call-backs for additional imaging.

For Ingred Prince, a rising junior at the University of Pennsylvania, some of her most enriching experiences have occurred through opportunities to study and explore abroad.

It’s a long way from DNA to RNA to protein, and only about two percent of a person’s genome is eventually converted into proteins.

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell’s energy factory. They report their findings this week in Cell.

Autoimmune disease occurs when the body's own natural defense system rebels against itself.  One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells. 

A team of researchers led by Penn Medicine anesthesiologists have pinpointed the “top five” most common perioperative procedures that are supported by the least amount of clinical evidence, in an effort to direct providers to make more cost-effective treatment decisions.

When a woman experiences a stressful event early in pregnancy, the risk of her child developing autism spectrum disorders or schizophrenia increases. Yet how maternal stress is transmitted to the brain of the developing fetus, leading to these problems in neurodevelopment, is poorly understood. 

Bringing clarity to a decades-long debate, a national team of researchers led by experts from the Perelman School of Medicine at the University of Pennsylvania has found that adding clot-busting medications known as thrombolytics to conventional approaches when treating sudden-onset pulmonary embolism patients is associated with 47 perce

Using powerful, newly developed cell culture and mouse  models of sporadic Parkinson’s disease (PD), a team of researchers from the Perelman School of Medicine at the University of Pennsylvania, has demonstrated that immunotherapy with specifically targeted antibodies may block the development and spread of PD pathology in the brain.