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Early immune clues could help detect and prevent type 1 diabetes
A teen takes a blood sugar reading with an app on their phone.

Image: Halfpoint Images via Getty Images

Early immune clues could help detect and prevent type 1 diabetes

Researchers from Penn Medicine have uncovered new clues in pancreas lymph nodes and the spleen that may stop the disease before insulin is lost forever.

Matt Toal

2 min. read

Florencia Polite: Healer, educator, advocate
Florencia Polite.

Florencia Polite, Penn Medicine’s chief of Academic Specialists in Obstetrics and Gynecology and vice chair of the department’s clinical operations.

(Image: Courtesy of Penn Medicine News)

Florencia Polite: Healer, educator, advocate

At home and overseas, Florencia Polite is on a mission to help patients and physicians understand how RSV vaccines protect newborns.

From Penn Medicine News

2 min. read

Amy Johnson: Pushing the boundaries of equine neurology
Amy Johnson with client horse Cartier.

Amy Johnson with client horse Cartier in New Bolton Center’s Equine Performance and Evaluation Facility arena.

nocred

Amy Johnson: Pushing the boundaries of equine neurology

Balancing clinical care with scientific inquiry, Penn Vet’s Amy Johnson leads efforts to decode the complexities of neurologic diseases in horses.

Martin Hackett

2 min. read

Investing in nurses reduces physician burnout

Investing in nurses reduces physician burnout

A landmark international study finds that hospitals with better nurse staffing and work environments not only benefits nurses but is significantly associated with less physician burnout and job dissatisfaction.

From Penn Nursing News

2 min. read

Identifying genes that keep cancer from spreading
Immunofluorescent view of a normal colon on the left and a colon tumor on the right.

Histopathology tissue sections of the normal colon (left) showing highly organized cell-cell junctions (red) and proliferative zones (green) in colonic crypts. In contrast, a colon adenocarcinoma (right) is highly disorganized, with inconsistent cell junctions that can ultimately contribute to metastatic dissemination.

(Image: Maggie Robertson)

Identifying genes that keep cancer from spreading

Using a novel approach, Penn Vet’s Chris Lengner and M. Andrés Blanco and colleagues have identified two genes that suppress colorectal cancer metastasis.

3 min. read

New CAR T strategy targets most common form of heart disease
a close-up view of a coronary artery with cholesterol plaque signifying cardiovascular disease and atherosclerosis

Kateryna Kon/Science Photo Library via Getty Images

New CAR T strategy targets most common form of heart disease

Preclinical research from investigators at Penn Medicine shows that experimental CAR T cells block inflammation in arteries, preventing more than two-thirds of the plaque buildup seen in untreated controls.

2 min. read