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NIH-funded canine immunotherapy data center charts a path toward transformative therapies
happy looking golden retriever in a clinic's kennel area

Researchers have learned much from treating dogs like Fantine, a golden retriever owned by Penn Vet supporter Richard Lichter, with immunotherapies for cancer, in part because tumors in dogs can closely resemble those in humans. With new support from the National Institutes of Health, a Penn-led team is ensuring such lessons can effectively translate into new therapeutic approaches. (Image: John Donges/Penn Vet)

NIH-funded canine immunotherapy data center charts a path toward transformative therapies

With support recently granted for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new insights in cancer care for people as well as pets.

Katherine Unger Baillie

Meeting a ‘generational challenge’: Feeding the world and doing it sustainably
cows in new bolton center pasture

(Homepage image) Cattle contribute a quarter of agriculture’s greenhouse gas emissions, yet animal protein can be an invaluable source of nutrition and way of combatting malnutrition around the globe. The new Center’s work is stepping into this tension, says Parsons, to address “a generational challenge.” (Image: Penn Vet)

Meeting a ‘generational challenge’: Feeding the world and doing it sustainably

With the launch of the Center for Stewardship Agriculture and Food Security, the School of Veterinary Medicine is working “to make animal agriculture part of a solution to a more resilient, sustainable, and equitable future.”

Katherine Unger Baillie

Making ‘true’ equine IVF a reproducible success
Three foals and two mares in a pasture

Making ‘true’ equine IVF a reproducible success

A new method developed by Katrin Hinrichs and colleagues in the School of Veterinary Medicine resulted in the birth of three healthy foals, opening the door to new insights in the basic biology of horse reproduction.

Katherine Unger Baillie

A decade of advancing working dogs for the greater good
new litter of penn working dogs

(Homepage image) Puppies at the Penn Vet Working Dog Center, like these black Labs of the “U litter,” begin their formal training at the tender age of 8 weeks, an unusual feature of the program. Playtime is an important part of that preparation, building confidence and improving physical and social skills.

A decade of advancing working dogs for the greater good

Inspired by her experience caring for working dogs following 9/11 at Ground Zero, Penn Vet Working Dog Center Director Cynthia Otto’s initial vision has grown into a thriving organization with a mission to use science to improve the breeding, training, care, and effectiveness of working dogs.

Katherine Unger Baillie

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response
Fluorescent microscopic image of three T cells surrounding a cancer cell

Tcells surround a cancer cell to finish it off, but such interactions do not always end with the T cells victorious. Researchers from Penn detail how cancer cells can prompt T cells to ingest bits of cancer cell membrane, a process known as trogocytosis. The cancer may evade immune detection as a result. (Image: Alex Ritter, Jennifer Lippincott Schwartz and Gillian Griffiths, National Institutes of Health)

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response

Blocking this process, known as trogocytosis, improved the ability of a CAR T cell therapy to treat cancer in mice, according to research led by School of Veterinary Medicine scientists.

Katherine Unger Baillie