Cancer most frequently spreads to the liver. Here’s why. Cancer most frequently spreads to the liver. Here’s why. Researchers from the Abramson Cancer Center shows hepatocytes, the chief functional cells of the liver, orchestrate the “seed and soil” process for cancer to spread to the liver.
For melanoma patients, one dose of immunotherapy before surgery can lead to remission A T cell expressing PD-1 (Image courtesy: Penn Medicine) For melanoma patients, one dose of immunotherapy before surgery can lead to remission An Abramson Cancer Center study finds that with a single dose of a PD-1 inhibitor, immune responses can peak in just one week.
Even cancer can’t get some patients to quit smoking. What could help them kick their habit? Penn In the News Philadelphia Inquirer Even cancer can’t get some patients to quit smoking. What could help them kick their habit? Robert Schnoll of the Perelman School of Medicine discussed his study on smoking cessation in cancer patients. “I’ve been working in nicotine dependence research for 20 years,” he said. “The brain chemistry is affected by decades of exposure to nicotine. Some patients view [smoking] as critical to managing the stress in their lives.” Cancer patients may need longer support to quit smoking Penn In the News Reuters Health Cancer patients may need longer support to quit smoking Robert Schnoll of the Perelman School of Medicine led a study that found that extending cessation support by an additional 12 weeks can help cancer patients quit smoking long-term. 25 years of integration, innovation, and ideals 25 years of integration, innovation, and ideals 2018 marked 25 years since the University of Pennsylvania Health System (UPHS) was first established—a milestone that would undoubtedly make the institution’s founder, Benjamin Franklin, proud. Energizing the immune system to eat cancer Energizing the immune system to eat cancer An Abramson Cancer Center study identifies a method of priming macrophages to boost an anti-tumor response wherein macrophages attack and eat cancer cells. Hindering melanoma metastasis with an FDA-approved drug In a mouse model, the FDA-approved drug reserpine seemed to hamper the ability of tumors to reshape distant tissues in ways that would encourage metastasis, for example, reducing the accumulation of fibronectin, a protein associated with certain types of cancer. Hindering melanoma metastasis with an FDA-approved drug A drug approved by the FDA 65 years ago for blood pressure control may aid in preventing cancer from spreading to distant organs. New research led by Serge Fuchs revealed that this drug disrupted formation of a fertile environment for metastasis by protecting healthy cells from harmful vesicles released by tumors. Resistance to cancer treatment is a chain reaction Skin tissue cancer cells Resistance to cancer treatment is a chain reaction A study identifies a chain reaction in cells that enables cancer to resist treatments that target BRAF mutations. Doctors can weigh in on brain tumors remotely Doctors can weigh in on brain tumors remotely Brain tumor patients will now have access to Penn Medicine’s cancer expertise through the new telemedicine second opinion program for brain tumors. CAR T cell therapy leads to lasting remissions CAR T cell therapy leads to lasting remissions In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor CAR T cell therapy Kymriah® led to long-lasting remissions in patients with non-Hodgkins lymphoma. Load More
Cancer patients may need longer support to quit smoking Penn In the News Reuters Health Cancer patients may need longer support to quit smoking Robert Schnoll of the Perelman School of Medicine led a study that found that extending cessation support by an additional 12 weeks can help cancer patients quit smoking long-term. 25 years of integration, innovation, and ideals 25 years of integration, innovation, and ideals 2018 marked 25 years since the University of Pennsylvania Health System (UPHS) was first established—a milestone that would undoubtedly make the institution’s founder, Benjamin Franklin, proud. Energizing the immune system to eat cancer Energizing the immune system to eat cancer An Abramson Cancer Center study identifies a method of priming macrophages to boost an anti-tumor response wherein macrophages attack and eat cancer cells. Hindering melanoma metastasis with an FDA-approved drug In a mouse model, the FDA-approved drug reserpine seemed to hamper the ability of tumors to reshape distant tissues in ways that would encourage metastasis, for example, reducing the accumulation of fibronectin, a protein associated with certain types of cancer. Hindering melanoma metastasis with an FDA-approved drug A drug approved by the FDA 65 years ago for blood pressure control may aid in preventing cancer from spreading to distant organs. New research led by Serge Fuchs revealed that this drug disrupted formation of a fertile environment for metastasis by protecting healthy cells from harmful vesicles released by tumors. Resistance to cancer treatment is a chain reaction Skin tissue cancer cells Resistance to cancer treatment is a chain reaction A study identifies a chain reaction in cells that enables cancer to resist treatments that target BRAF mutations. Doctors can weigh in on brain tumors remotely Doctors can weigh in on brain tumors remotely Brain tumor patients will now have access to Penn Medicine’s cancer expertise through the new telemedicine second opinion program for brain tumors. CAR T cell therapy leads to lasting remissions CAR T cell therapy leads to lasting remissions In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor CAR T cell therapy Kymriah® led to long-lasting remissions in patients with non-Hodgkins lymphoma.
25 years of integration, innovation, and ideals 25 years of integration, innovation, and ideals 2018 marked 25 years since the University of Pennsylvania Health System (UPHS) was first established—a milestone that would undoubtedly make the institution’s founder, Benjamin Franklin, proud.
Energizing the immune system to eat cancer Energizing the immune system to eat cancer An Abramson Cancer Center study identifies a method of priming macrophages to boost an anti-tumor response wherein macrophages attack and eat cancer cells.
Hindering melanoma metastasis with an FDA-approved drug In a mouse model, the FDA-approved drug reserpine seemed to hamper the ability of tumors to reshape distant tissues in ways that would encourage metastasis, for example, reducing the accumulation of fibronectin, a protein associated with certain types of cancer. Hindering melanoma metastasis with an FDA-approved drug A drug approved by the FDA 65 years ago for blood pressure control may aid in preventing cancer from spreading to distant organs. New research led by Serge Fuchs revealed that this drug disrupted formation of a fertile environment for metastasis by protecting healthy cells from harmful vesicles released by tumors.
Resistance to cancer treatment is a chain reaction Skin tissue cancer cells Resistance to cancer treatment is a chain reaction A study identifies a chain reaction in cells that enables cancer to resist treatments that target BRAF mutations.
Doctors can weigh in on brain tumors remotely Doctors can weigh in on brain tumors remotely Brain tumor patients will now have access to Penn Medicine’s cancer expertise through the new telemedicine second opinion program for brain tumors.
CAR T cell therapy leads to lasting remissions CAR T cell therapy leads to lasting remissions In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor CAR T cell therapy Kymriah® led to long-lasting remissions in patients with non-Hodgkins lymphoma.