Cancer Research

Directional sign for Perelman Center for Advanced Medicine Abramson Cancer Center 3400 Civic Center Blvd.

Off-the-shelf immunotherapy can bring lymphoma patients closer to remission

A Penn study shows the promise of an off-the-shelf immunotherapy in relapse/refractory non-Hodgkin lymphoma, even when CAR T therapy fails.

rendering of the microbiome inside the gut

The new tool in fighting cancer: Antibiotics

The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy.

Microscopic slices of tumor on a glass slide

Researchers identify method to slow down cancer cells efforts to multiply

A study from the Abramson Cancer Center finds that turning on a key metabolic process could make soft tissue sarcoma more susceptible to treatment.

Kill stomach cancer risk by attacking this common bacteria

Penn researchers are the first to assess Helicobacter pylori infection and gastric cancer risk among certain demographics and ethnic groups.

Positive results in first-in-U.S. trial of CRISPR-edited immune cells

Genetically editing a cancer patient’s immune cells using CRISPR/Cas9 technology, then infusing those cells back into the patient appears safe and feasible based on early data from the first-ever clinical trial to test the approach in humans in the United States.

To monitor cancer therapy, researchers tag CAR T cells with imaging markers

With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. Now scientists have now discovered a new way to track CAR T cells in the body.

MRI scan of brain and hand with a red marker pointing at a mark on the scan.

Blood test can predict prognosis in deadly brain cancer

A Penn study points to clinical utility of liquid biopsy in glioblastoma, allowing doctors the ability to measure the progression of the cancer based on the amount of cell-free DNA in the bloodstream

Cancer patient in wheelchair being pushed by a caregiver who consults with doctor holding a medical chart.

Algorithm identifies advance care planning needs

A Penn-developed system can be used to ensure that doctors talk to cancer patients about their values and goals before it is too late.

Basser Center takes aim at BRCA

Twenty-five years after the discovery of genetic mutations that dramatically increase cancer risk, the Penn Medicine’s Basser Center for BRCA is building scientific knowledge alongside public awareness about BRCA-related cancers.

computer rendering of microscopic images of DNA helix on the left, a tumor on the right.

Algorithm personalizes which cancer mutations are best targets for immunotherapy

A new model developed by researchers in the Abramson Cancer Center hand-picks cancer cells to target for more effective, customized cancer vaccines.

Filters