Cancer Research | Penn Today

Two people side by side in different images. In the one on the left, the person stands in an office and a blue suit, hands crossed low in front. In the one on the right is a person in a tie and white coat that reads, "Carl H. June, M.D. Abramson Cancer Center"

Kathleen Hall Jamieson, Carl June elected to National Academy of Sciences

The researchers, from the Annenberg Public Policy Center and the Perelman School of Medicine, join a class of honored scholars recognized for their unique and ongoing contributions to original research.

Gloved hand holds a vial of blood for a blood test

Blood test may help doctors catch pancreatic cancer early

A blood test may be able to detect the most common form of pancreatic cancer while it is still in its early stages while also helping doctors accurately stage a patient’s disease and guide them to the appropriate treatment.

Fluorescent microscopic image shows mammary gland cells

Tailoring treatment for triple-negative breast cancer

Research led by the School of Veterinary Medicine’s Rumela Chakrabarti identified a molecular pathway responsible for the disease’s progression and spread.

Microscopic rendering of DNA helix repairing itself

PARP inhibitor drugs can be ‘tuned’ for better killing of tumor cells

Using innovative techniques, a new Penn Medicine study helps clear up mystery about why PARP-inhibiting compounds vary so much in their clinical effectiveness

Rendering of a field of cells, macrophages above attack the cells

Alternative immune cells may surpass T cells to fight solid tumors

Penn researchers have shown success using genetically engineered macrophages, an immune cell that eats invaders in the body, to target solid tumors.

Penn is fighting pancreatic cancer

Researchers within the Penn Pancreatic Research Center and beyond continue to seek innovative ways to treat and detect this deadly disease—and are making promising progress.

A lab worker wearing latex gloves holds a vial of blood in a lab

A new way to predict lung cancer treatment response: The blood test

A Penn study shows a better clinical response to immunotherapy correlates with higher ratio of tumor mutations detected by a liquid biopsy.

woman with clasped hands stands in a stairwell with colorful art in the background

Working on ‘the human side’ of heritable cancers

How do you talk about cancer risk? How do you make major life decisions knowing you are likely to develop cancer? Allison Werner-Lin looks at these questions, studying the intersection of genetics and family life.

rendering of DNA sequence and cells as part of gene editing from CRISPR cas9

CRISPR-edited immune cells can survive and thrive after infusion into cancer patients

In the first U.S. clinical trial, cells removed from patients and brought back into the lab were able to kill cancer months after their original manufacturing and infusion.

CRISPR cancer trial finds that gene-edited immune cells are safe

Edward Stadtmauer and Carl June of the Perelman School of Medicine spoke about a clinical trial that found it safe to inject CRISPR gene-edited immune cells into people with advanced cancer.

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