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Bioengineering technology keeps track of living cells and tissues
Fluorescent markers highlighting individual cells.

A new chemistry technique developed by Jina Ko introduces a method for multiplexed temporospatial imaging of living cells with immunofluorescence. (Image: Penn Engineering Today)

Bioengineering technology keeps track of living cells and tissues

A new chemistry technique developed by Jina Ko, assistant bioengineering professor, and colleagues allows for a wider range of fluorescent markers to be added to individual cells without damaging them in the process.

From Penn Engineering Today

Managing mental health amid gun violence
A large grassy area covered in a display of t-shirts erected with names of people killed by gun violence around a sign that reads MEMORIAL TO PHILADELPHIANS MURDERED BY ILLEGAL GUNS.

Image: Michael Stokes via Flickr

Managing mental health amid gun violence

In 2021, Philadelphia saw a record number of 486 homicides by shooting as well 1,846 non-fatal shootings. According to clinical psychologist Leah Blain, exposure to trauma, including to gun violence, increases the risk of negative health outcomes.

From Penn Medicine News

Children younger than 5 eligible for COVID-19 vaccines
An adult wearing a mask squatting next to a child wearing a mask at the end of a slide on an outdoor playground.

Children younger than 5 eligible for COVID-19 vaccines

In a Q&A, Lori Handy of Penn Medicine and CHOP discusses what it means now that this final group can get protection, plus offers recommendations for families with concerns about doing so.

Michele W. Berger

A newly identified stem cell regulator enables lifelong sperm production
Illustration of different cell types that eventually give rise to sperm shows that blocking an early stage of cell development can prevent the formation of sperm

When the enzyme DOT1L is not functional, spermatogonial stem cells become exhausted, leading to a failure of sperm cell development. This crucial role for DOT1L places it in rarefied company as one of just a handful of known stem cell self-renewal factors, a Penn Vet team found. (Image: Courtesy of Jeremy Wang)

A newly identified stem cell regulator enables lifelong sperm production

Research led by Jeremy Wang of the School of Veterinary Medicine has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.

Katherine Unger Baillie

University of Pennsylvania’s first NFT commemorates mRNA research
Lots of gold blobs, some larger and closer to the front of the image, some smaller and farther away, on a pinkish background.

A still image from the 3D animated video component of the non-fungible token, which will also include patent documents and a letter from Drew Weissman of Penn Medicine. (Image: Courtesy Penn Medicine and Christie’s)

University of Pennsylvania’s first NFT commemorates mRNA research

Proceeds from the July auction of the non-fungible token—a digital asset—will benefit ongoing research at Penn.

Penn Medicine , Brandon Lausch , Peter Winicov

Text messaging shows promise in reaching unvaccinated patients
Hands texting on a smartphone.

nocred

Text messaging shows promise in reaching unvaccinated patients

A Penn study finds that while automated texting did not get more patients to get their vaccinations against COVID-19, it reached roughly the same amount as manned phone calls.

From Penn Medicine News

Parental nicotine use and addiction risk for children
A put-out cigarette standing on its end, next to half of another crumpled cigarette. In the background are two whole cigarettes.

Parental nicotine use and addiction risk for children

In research done using rats, Penn Nursing’s Heath Schmidt and colleagues found that males that engaged in voluntary nicotine use had offspring more likely to do so, too. Some offspring also developed impaired memory and anxiety-like behavior.

Michele W. Berger