Image: Dr. Paul Akhigbe (Courtesy of Modupe Coker)
Early challenges to the immune system disrupt oral health
Modupe O. Coker from the School of Dental Medicine and a collaborative team of researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.
Image: Ten Image/Science Photo Library via Getty Images
Genetic testing beneficial in critically ill adults
Penn Medicine researchers have identified genetic conditions in a large percent of adults admitted to the intensive care unit, dispelling the belief that genetic testing only benefits a pediatric population.
The actual chip of human leukemia bone marrow where chambers and channels were filled with food dyes.
(Image: NYU Tandon Applied Micro-Bioengineering Laboratory/Courtesy of Weiqiang Chen)
Transforming CAR T treatment: ‘Leukemia-on-a-chip’
In a collaborative effort with NYU, Penn researchers have helped pioneer a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.
As part of the Pennsylvania Animal Diagnostic Laboratory System (PADLS), Penn Vet’s New Bolton Center helps to protect animals and humans from health threats and minimize agricultural economic loss.
Food waste: Recycling, not discarding, offers huge environmental benefits
Researchers at Penn Vet examine how common food waste recycling methods, including composting, could have a big impact on greenhouse gas emissions and the use of natural resources.
Raghavi Sudharsan and William Beltran of the Division of Experimental Retinal Therapies at Penn’s School of Veterinary Medicine.
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New tools to treat retinal degenerations at advanced stages of disease
A collaborative team of researchers led by vision scientists at the School of Veterinary Medicine have developed novel promoters that drive strong and specific gene expression in rod and cone photoreceptors in mid-to-late stages of disease, potentially offering new and improved options for gene therapy.
Soon-to-be-graduate hopes to deliver primary care to rural communities
Fueled by his faith, Chip Chambers, a fifth-year M.D./M.B.A. student in the Perelman School of Medicine and Wharton School, has always looked for ways to serve.“My faith is a huge motivator of everything that I do. I just believe that I’ve been blessed with a lot of things that I didn’t earn and that I have a responsibility to steward those for the good of other people and not for myself,” Chambers says.
Kendra Domotor may have “zigzagged” her way to dentistry, but her journey helped her find her center in dentistry, helping her blend her love of science, teaching, and service.
Image: Kevin Monko; Courtesy of Penn Dental Medicine.
A better understanding of common hypertension medications
Henry Daniell of Penn Dental and collaborators found that ACE inhibitors dramatically reduced the activity of ACE2, a critical cardioprotective enzyme.
